Pubmed for links to articles
Kumar M, Bowers RR, Delaney JR. (2020) Single-cell analysis of copy-number alterations in serous ovarian cancer reveals substantial heterogeneity in both low- and high-grade tumors. Cell Cycle. Link to publication.
Delaney JR#, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR#, Stupack DG#. (2020) Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLOS Genet. Link to publication. Link to CAIRN Shiny App.
Ortell KO, Switonski PM, Delaney JR. (2019) FairSubset: A tool to choose representative subsets of data for use with replicates or groups of different sample sizes. J Biol Methods. Link to publication. Link to Shiny App.
Delaney JR#, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, . . . , Schlaepfer DD, Harismendy O, Stupack DG#. (2017) Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun.
Axelrod J, Delaney JR. (2017) Pathways to Genome-targeted Therapies in Serous Ovarian Cancer. Journal of Nature and Science.
Delaney JR#, Stupack DG#. (2017, invited Editorial) Using genetics to develop new treatment possibilities for ovarian cancer. Int J Endocr Oncol
Delaney, J. R., Stupack, D. (2016) Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas. PLoS One.
Davis, M.A.*, Delaney, J. R.*, Patel, C. P., Storgard, R., Stupack, D. G. (2016) Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther.
McCormick, M. A.*, Delaney, J. R.*, Tsuchiya, M., Tsuchiyama, S., Shemorry, A., Sim, S., . . . Kennedy, B. K. (2015). A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metab, 22(5), 895-906. doi:10.1016/j.cmet.2015.09.008
Young, S. A., McCabe, K. E., Bartakova, A., Delaney, J. R., Pizzo, D. P., Newbury, R. O., . . . Stupack, D. G. (2015). Integrin alpha4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS One, 10(5), e0120815. doi:10.1371/journal.pone.0120815
Delaney, J. R., Patel, C., McCabe, K. E., Lu, D., Davis, M. A., Tancioni, I., . . . Stupack, D. G. (2015). A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget, 6(31), 31104-31118. doi:10.18632/oncotarget.5093
Zhao, W., Fang, B. X., Niu, Y. J., Liu, Y. N., Liu, B., Delaney J. R., . . . Liu, X. G. (2014). Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase. Mech Ageing Dev, 138, 53-58. doi:10.1016/j.mad.2014.01.007
McCabe, K. E., Bacos, K., Lu, D., Delaney, J. R., Axelrod, J., Potter, M. D., . . . Stupack, D. G. (2014). Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis, 5, e1496. doi:10.1038/cddis.2014.448
Sutphin, G. L.*, Delaney, J. R.*, & Kaeberlein, M. (2014). Replicative life span analysis in budding yeast. Methods Mol Biol, 1205, 341-357. doi:10.1007/978-1-4939-1363-3_20
Labunskyy, V. M., Gerashchenko, M. V., Delaney, J. R., Kaya, A., Kennedy, B. K., Kaeberlein, M., & Gladyshev, V. N. (2014). Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet, 10(1), e1004019. doi:10.1371/journal.pgen.1004019
Schleit, J., Johnson, S. C., Bennett, C. F., Simko, M., Trongtham, N., Delaney, J. R., . . . Kaeberlein, M. (2013). Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell, 12(6), 1050-1061. doi:10.1111/acel.12130
Delaney, J. R.*, Murakami, C.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2013). Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. Exp Gerontol, 48(10), 1006-1013. doi:10.1016/j.exger.2012.12.001
Delaney, J. R., Chou, A., Olsen, B., Carr, D., Murakami, C., Ahmed, U., . . . Kaeberlein, M. (2013). End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging. FEMS Yeast Res, 13(3), 267-276. doi:10.1111/1567-1364.12030
Delaney, J. R., Ahmed, U., Chou, A., Sim, S., Carr, D., Murakami, C. J., . . . Kaeberlein, M. (2013). Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell, 12(1), 156-166. doi:10.1111/acel.12032
Steffen, K. K., McCormick, M. A., Pham, K. M., MacKay, V. L., Delaney, J. R., Murakami, C. J., . . . Kennedy, B. K. (2012). Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae. Genetics, 191(1), 107-118. doi:10.1534/genetics.111.136549
Murakami, C.*, Delaney, J. R.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2012). pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. Cell Cycle, 11(16), 3087-3096. doi:10.4161/cc.21465
Kruegel, U., Robison, B., Dange, T., Kahlert, G., Delaney, J. R., Kotireddy, S., . . . Schmidt, M. (2011). Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet, 7(9), e1002253. doi:10.1371/journal.pgen.1002253
Delaney, J. R.*, Sutphin, G. L.*, Dulken, B., Sim, S., Kim, J. R., Robison, B., . . . Kaeberlein, M. (2011). Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell, 10(6), 1089-1091. doi:10.1111/j.1474-9726.2011.00742.x
Delaney, J. R., Murakami, C. J., Olsen, B., Kennedy, B. K., & Kaeberlein, M. (2011). Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle, 10(1), 156-165. doi:10.4161/cc.10.1.14457
Zhu, L., Zhou, R., Mettler, S., Wu, T., Abbas, A., Delaney, J. R., & Forte, J. G. (2007). High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function. Am J Physiol Cell Physiol, 293(3), C874-884. doi:10.1152/ajpcell.00111.2007
Delaney JR#, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR#, Stupack DG#. (2020) Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLOS Genet. Link to publication. Link to CAIRN Shiny App.
Ortell KO, Switonski PM, Delaney JR. (2019) FairSubset: A tool to choose representative subsets of data for use with replicates or groups of different sample sizes. J Biol Methods. Link to publication. Link to Shiny App.
Delaney JR#, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, . . . , Schlaepfer DD, Harismendy O, Stupack DG#. (2017) Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun.
Axelrod J, Delaney JR. (2017) Pathways to Genome-targeted Therapies in Serous Ovarian Cancer. Journal of Nature and Science.
Delaney JR#, Stupack DG#. (2017, invited Editorial) Using genetics to develop new treatment possibilities for ovarian cancer. Int J Endocr Oncol
Delaney, J. R., Stupack, D. (2016) Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas. PLoS One.
Davis, M.A.*, Delaney, J. R.*, Patel, C. P., Storgard, R., Stupack, D. G. (2016) Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther.
McCormick, M. A.*, Delaney, J. R.*, Tsuchiya, M., Tsuchiyama, S., Shemorry, A., Sim, S., . . . Kennedy, B. K. (2015). A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metab, 22(5), 895-906. doi:10.1016/j.cmet.2015.09.008
Young, S. A., McCabe, K. E., Bartakova, A., Delaney, J. R., Pizzo, D. P., Newbury, R. O., . . . Stupack, D. G. (2015). Integrin alpha4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS One, 10(5), e0120815. doi:10.1371/journal.pone.0120815
Delaney, J. R., Patel, C., McCabe, K. E., Lu, D., Davis, M. A., Tancioni, I., . . . Stupack, D. G. (2015). A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget, 6(31), 31104-31118. doi:10.18632/oncotarget.5093
Zhao, W., Fang, B. X., Niu, Y. J., Liu, Y. N., Liu, B., Delaney J. R., . . . Liu, X. G. (2014). Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase. Mech Ageing Dev, 138, 53-58. doi:10.1016/j.mad.2014.01.007
McCabe, K. E., Bacos, K., Lu, D., Delaney, J. R., Axelrod, J., Potter, M. D., . . . Stupack, D. G. (2014). Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis, 5, e1496. doi:10.1038/cddis.2014.448
Sutphin, G. L.*, Delaney, J. R.*, & Kaeberlein, M. (2014). Replicative life span analysis in budding yeast. Methods Mol Biol, 1205, 341-357. doi:10.1007/978-1-4939-1363-3_20
Labunskyy, V. M., Gerashchenko, M. V., Delaney, J. R., Kaya, A., Kennedy, B. K., Kaeberlein, M., & Gladyshev, V. N. (2014). Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet, 10(1), e1004019. doi:10.1371/journal.pgen.1004019
Schleit, J., Johnson, S. C., Bennett, C. F., Simko, M., Trongtham, N., Delaney, J. R., . . . Kaeberlein, M. (2013). Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell, 12(6), 1050-1061. doi:10.1111/acel.12130
Delaney, J. R.*, Murakami, C.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2013). Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. Exp Gerontol, 48(10), 1006-1013. doi:10.1016/j.exger.2012.12.001
Delaney, J. R., Chou, A., Olsen, B., Carr, D., Murakami, C., Ahmed, U., . . . Kaeberlein, M. (2013). End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging. FEMS Yeast Res, 13(3), 267-276. doi:10.1111/1567-1364.12030
Delaney, J. R., Ahmed, U., Chou, A., Sim, S., Carr, D., Murakami, C. J., . . . Kaeberlein, M. (2013). Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell, 12(1), 156-166. doi:10.1111/acel.12032
Steffen, K. K., McCormick, M. A., Pham, K. M., MacKay, V. L., Delaney, J. R., Murakami, C. J., . . . Kennedy, B. K. (2012). Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae. Genetics, 191(1), 107-118. doi:10.1534/genetics.111.136549
Murakami, C.*, Delaney, J. R.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2012). pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. Cell Cycle, 11(16), 3087-3096. doi:10.4161/cc.21465
Kruegel, U., Robison, B., Dange, T., Kahlert, G., Delaney, J. R., Kotireddy, S., . . . Schmidt, M. (2011). Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet, 7(9), e1002253. doi:10.1371/journal.pgen.1002253
Delaney, J. R.*, Sutphin, G. L.*, Dulken, B., Sim, S., Kim, J. R., Robison, B., . . . Kaeberlein, M. (2011). Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell, 10(6), 1089-1091. doi:10.1111/j.1474-9726.2011.00742.x
Delaney, J. R., Murakami, C. J., Olsen, B., Kennedy, B. K., & Kaeberlein, M. (2011). Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle, 10(1), 156-165. doi:10.4161/cc.10.1.14457
Zhu, L., Zhou, R., Mettler, S., Wu, T., Abbas, A., Delaney, J. R., & Forte, J. G. (2007). High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function. Am J Physiol Cell Physiol, 293(3), C874-884. doi:10.1152/ajpcell.00111.2007
Book
A sci-fi novel written in my college years: Trojan Cure
A sci-fi novel written in my college years: Trojan Cure