Pubmed for links to articles
Delaney JR, La Spada AR. (2023) Protocol for mapping double-stranded DNA break sites across the genome with translocation capture sequencing. STAR Protoc. (Cell Press). Link to publication.
Helke KL, Gudi RR, Vasu C, Delaney JR. (2022) Combination of Autophagy Selective Therapeutics With Doxil: An Assessment of Pathological Toxicity. Front. Toxicol. Link to publication.
Bowers RR, Andrade MF, Jones CM, White-Gilbertson S, Voelkel-Johnson C, Delaney JR. (2022) Autophagy modulating therapeutics inhibit ovarian cancer colony generation by polyploid giant cancer cells (PGCCs). BMC Cancer. Link to publication
Bowers RR*, Jones CM*, Paz EA, Barrows JK, Armeson KE, Long DT, Delaney JR. (2022) SWAN Pathway-Network Identification of Common Aneuploidy-Based Oncogenic Drivers. Nucleic Acids Research. Link to publication
Recognized on the Wall of Science by Dean Steyer as the recipient of the College of Medicine High Impact Scientific Publication Award
Delaney JR. (2021) Aneuploidy: An opportunity within single-cell RNA sequencing analysis. BIOCELL. Link to publication
Klionsky DJ, [1,000+ autophagy authors], Delaney JR, [1,000+ autophagy authors], Brand-Saberi B, Dong XC, Kenchappa CS, Li Z, Lin Y, Oshima S, Rong Y, Sluimer JC, Stallings CL, Tong CK. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. Link to publication
Kumar M, Bowers RR, Delaney JR. (2020) Single-cell analysis of copy-number alterations in serous ovarian cancer reveals substantial heterogeneity in both low- and high-grade tumors. Cell Cycle. Link to publication
Delaney JR#, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR#, Stupack DG#. (2020) Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLOS Genet. Link to publication. Link to CAIRN Shiny App
Ortell KO, Switonski PM, Delaney JR. (2019) FairSubset: A tool to choose representative subsets of data for use with replicates or groups of different sample sizes. J Biol Methods. Link to publication. Link to Shiny App
Delaney JR#, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, . . . , Schlaepfer DD, Harismendy O, Stupack DG#. (2017) Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. Link to publication
Axelrod J, Delaney JR. (2017) Pathways to Genome-targeted Therapies in Serous Ovarian Cancer. Journal of Nature and Science. Link to publication
Delaney JR#, Stupack DG#. (2017, invited Editorial) Using genetics to develop new treatment possibilities for ovarian cancer. Int J Endocr Oncol. Link to publication
Delaney, J. R., Stupack, D. (2016) Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas. PLoS One. Link to publication
Davis, M.A.*, Delaney, J. R.*, Patel, C. P., Storgard, R., Stupack, D. G. (2016) Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. Link to publication
McCormick, M. A.*, Delaney, J. R.*, Tsuchiya, M., Tsuchiyama, S., Shemorry, A., Sim, S., . . . Kennedy, B. K. (2015). A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metab, Link to publication
Young, S. A., McCabe, K. E., Bartakova, A., Delaney, J. R., Pizzo, D. P., Newbury, R. O., . . . Stupack, D. G. (2015). Integrin alpha4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS One, Link to publication
Delaney, J. R., Patel, C., McCabe, K. E., Lu, D., Davis, M. A., Tancioni, I., . . . Stupack, D. G. (2015). A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget. Link to publication
Zhao, W., Fang, B. X., Niu, Y. J., Liu, Y. N., Liu, B., Delaney J. R., . . . Liu, X. G. (2014). Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase. Mech Ageing Dev, 138, 53-58. doi:10.1016/j.mad.2014.01.007
McCabe, K. E., Bacos, K., Lu, D., Delaney, J. R., Axelrod, J., Potter, M. D., . . . Stupack, D. G. (2014). Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis, 5, e1496. doi:10.1038/cddis.2014.448
Sutphin, G. L.*, Delaney, J. R.*, & Kaeberlein, M. (2014). Replicative life span analysis in budding yeast. Methods Mol Biol. Link to publication
Labunskyy, V. M., Gerashchenko, M. V., Delaney, J. R., Kaya, A., Kennedy, B. K., Kaeberlein, M., & Gladyshev, V. N. (2014). Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet, 10(1), e1004019. doi:10.1371/journal.pgen.1004019
Schleit, J., Johnson, S. C., Bennett, C. F., Simko, M., Trongtham, N., Delaney, J. R., . . . Kaeberlein, M. (2013). Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell, 12(6), 1050-1061. doi:10.1111/acel.12130
Delaney, J. R.*, Murakami, C.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2013). Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. Exp Gerontol. Link to publication
Delaney, J. R., Chou, A., Olsen, B., Carr, D., Murakami, C., Ahmed, U., . . . Kaeberlein, M. (2013). End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging. FEMS Yeast Res. Link to publication
Delaney, J. R., Ahmed, U., Chou, A., Sim, S., Carr, D., Murakami, C. J., . . . Kaeberlein, M. (2013). Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell. Link to publication
Steffen, K. K., McCormick, M. A., Pham, K. M., MacKay, V. L., Delaney, J. R., Murakami, C. J., . . . Kennedy, B. K. (2012). Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae. Genetics. Link to publication
Murakami, C.*, Delaney, J. R.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2012). pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. Cell Cycle. Link to publication
Kruegel, U., Robison, B., Dange, T., Kahlert, G., Delaney, J. R., Kotireddy, S., . . . Schmidt, M. (2011). Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet. Link to publication
Delaney, J. R.*, Sutphin, G. L.*, Dulken, B., Sim, S., Kim, J. R., Robison, B., . . . Kaeberlein, M. (2011). Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell. Link to publication
Delaney, J. R., Murakami, C. J., Olsen, B., Kennedy, B. K., & Kaeberlein, M. (2011). Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle. Link to publication
Zhu, L., Zhou, R., Mettler, S., Wu, T., Abbas, A., Delaney, J. R., & Forte, J. G. (2007). High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function. Am J Physiol Cell Physiol. Link to publication
Helke KL, Gudi RR, Vasu C, Delaney JR. (2022) Combination of Autophagy Selective Therapeutics With Doxil: An Assessment of Pathological Toxicity. Front. Toxicol. Link to publication.
Bowers RR, Andrade MF, Jones CM, White-Gilbertson S, Voelkel-Johnson C, Delaney JR. (2022) Autophagy modulating therapeutics inhibit ovarian cancer colony generation by polyploid giant cancer cells (PGCCs). BMC Cancer. Link to publication
Bowers RR*, Jones CM*, Paz EA, Barrows JK, Armeson KE, Long DT, Delaney JR. (2022) SWAN Pathway-Network Identification of Common Aneuploidy-Based Oncogenic Drivers. Nucleic Acids Research. Link to publication
Recognized on the Wall of Science by Dean Steyer as the recipient of the College of Medicine High Impact Scientific Publication Award
Delaney JR. (2021) Aneuploidy: An opportunity within single-cell RNA sequencing analysis. BIOCELL. Link to publication
Klionsky DJ, [1,000+ autophagy authors], Delaney JR, [1,000+ autophagy authors], Brand-Saberi B, Dong XC, Kenchappa CS, Li Z, Lin Y, Oshima S, Rong Y, Sluimer JC, Stallings CL, Tong CK. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. Link to publication
Kumar M, Bowers RR, Delaney JR. (2020) Single-cell analysis of copy-number alterations in serous ovarian cancer reveals substantial heterogeneity in both low- and high-grade tumors. Cell Cycle. Link to publication
Delaney JR#, Patel CB, Bapat J, Jones CM, Ramos-Zapatero M, Ortell KK, Tanios R, Haghighiabyaneh M, Axelrod J, DeStefano JW, Tancioni I, Schlaepfer DD, Harismendy O, La Spada AR#, Stupack DG#. (2020) Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. PLOS Genet. Link to publication. Link to CAIRN Shiny App
Ortell KO, Switonski PM, Delaney JR. (2019) FairSubset: A tool to choose representative subsets of data for use with replicates or groups of different sample sizes. J Biol Methods. Link to publication. Link to Shiny App
Delaney JR#, Patel CB, Willis KM, Haghighiabyaneh M, Axelrod J, . . . , Schlaepfer DD, Harismendy O, Stupack DG#. (2017) Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. Link to publication
Axelrod J, Delaney JR. (2017) Pathways to Genome-targeted Therapies in Serous Ovarian Cancer. Journal of Nature and Science. Link to publication
Delaney JR#, Stupack DG#. (2017, invited Editorial) Using genetics to develop new treatment possibilities for ovarian cancer. Int J Endocr Oncol. Link to publication
Delaney, J. R., Stupack, D. (2016) Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas. PLoS One. Link to publication
Davis, M.A.*, Delaney, J. R.*, Patel, C. P., Storgard, R., Stupack, D. G. (2016) Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. Link to publication
McCormick, M. A.*, Delaney, J. R.*, Tsuchiya, M., Tsuchiyama, S., Shemorry, A., Sim, S., . . . Kennedy, B. K. (2015). A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metab, Link to publication
Young, S. A., McCabe, K. E., Bartakova, A., Delaney, J. R., Pizzo, D. P., Newbury, R. O., . . . Stupack, D. G. (2015). Integrin alpha4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma. PLoS One, Link to publication
Delaney, J. R., Patel, C., McCabe, K. E., Lu, D., Davis, M. A., Tancioni, I., . . . Stupack, D. G. (2015). A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. Oncotarget. Link to publication
Zhao, W., Fang, B. X., Niu, Y. J., Liu, Y. N., Liu, B., Delaney J. R., . . . Liu, X. G. (2014). Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase. Mech Ageing Dev, 138, 53-58. doi:10.1016/j.mad.2014.01.007
McCabe, K. E., Bacos, K., Lu, D., Delaney, J. R., Axelrod, J., Potter, M. D., . . . Stupack, D. G. (2014). Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis, 5, e1496. doi:10.1038/cddis.2014.448
Sutphin, G. L.*, Delaney, J. R.*, & Kaeberlein, M. (2014). Replicative life span analysis in budding yeast. Methods Mol Biol. Link to publication
Labunskyy, V. M., Gerashchenko, M. V., Delaney, J. R., Kaya, A., Kennedy, B. K., Kaeberlein, M., & Gladyshev, V. N. (2014). Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet, 10(1), e1004019. doi:10.1371/journal.pgen.1004019
Schleit, J., Johnson, S. C., Bennett, C. F., Simko, M., Trongtham, N., Delaney, J. R., . . . Kaeberlein, M. (2013). Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell, 12(6), 1050-1061. doi:10.1111/acel.12130
Delaney, J. R.*, Murakami, C.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2013). Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. Exp Gerontol. Link to publication
Delaney, J. R., Chou, A., Olsen, B., Carr, D., Murakami, C., Ahmed, U., . . . Kaeberlein, M. (2013). End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging. FEMS Yeast Res. Link to publication
Delaney, J. R., Ahmed, U., Chou, A., Sim, S., Carr, D., Murakami, C. J., . . . Kaeberlein, M. (2013). Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell. Link to publication
Steffen, K. K., McCormick, M. A., Pham, K. M., MacKay, V. L., Delaney, J. R., Murakami, C. J., . . . Kennedy, B. K. (2012). Ribosome deficiency protects against ER stress in Saccharomyces cerevisiae. Genetics. Link to publication
Murakami, C.*, Delaney, J. R.*, Chou, A., Carr, D., Schleit, J., Sutphin, G. L., . . . Kaeberlein, M. (2012). pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. Cell Cycle. Link to publication
Kruegel, U., Robison, B., Dange, T., Kahlert, G., Delaney, J. R., Kotireddy, S., . . . Schmidt, M. (2011). Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet. Link to publication
Delaney, J. R.*, Sutphin, G. L.*, Dulken, B., Sim, S., Kim, J. R., Robison, B., . . . Kaeberlein, M. (2011). Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell. Link to publication
Delaney, J. R., Murakami, C. J., Olsen, B., Kennedy, B. K., & Kaeberlein, M. (2011). Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast. Cell Cycle. Link to publication
Zhu, L., Zhou, R., Mettler, S., Wu, T., Abbas, A., Delaney, J. R., & Forte, J. G. (2007). High turnover of ezrin T567 phosphorylation: conformation, activity, and cellular function. Am J Physiol Cell Physiol. Link to publication
Book
A [comically terrible] sci-fi novel written in my college years: Trojan Cure
A [comically terrible] sci-fi novel written in my college years: Trojan Cure