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Mirna Mina-Abouda, M.S.Ph.D. StudentSCIENCE Mirna is investigating cadmium-sequestering metallothionein proteins and evaluating their previously uncharacterized tumor suppressor phenotypes. She is evaluating metabolic and signal transduction pathways altered in low vs. high metallothionein cancer cells, using carefully controlled genetic models.
HOBBY Mirna likes to take her dog to the park, do yoga, cook Mediterranean food, and travel with her husband |
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Wendy Zhang, B.S.Masters in Biomedical Sciences StudentSCIENCE Wendy is investigating critical genes involved in the polyploid giant cancer cell lifecycle in ovarian cancers. She is utilizing CRISPR-Cas9, image flow cytometry, live cell microscopy, and other advanced techniques to pinpoint vulnerabilities within the chemotherapy-resistant cell population.
HOBBY Wendy enjoys watching the sunset, tv, and occasionally reading |
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Rachel Choe, B.S.Research SpecialistSCIENCE Rachel is investigating cadmium-sequestering metallothionein proteins and evaluating their previously uncharacterized tumor suppressor phenotypes. She is building off of past research in the Delaney lab that established the role of aneuploid-suppressed autophagy as a targetable vulnerability of ovarian cancer, as metallothionein tumor suppression is also suppressed by aneuploidy. Rachel is working with our newly developed mouse model Trp53em1Jdel_Tg(Ovgp1-Trp53*R270H-Myc) and breeding mice to develop transgenic mice with metallothionein knockdowns to access how metallothionein knockdown contributes to tumor development and novel vulnerabilities in transgenic mice.
HOBBY Rachel likes to sit outside to read books and opinion pieces and find coffee shops |
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Isabella BerryUndergraduate Researcher, College of CharlestonSCIENCE Isabella is researching cadmium-sequestering metallothionein proteins and evaluating their previously uncharacterized tumor suppressor phenotypes. She is evaluating mitochondria characteristics through the uses of western blots and immunofluorescence on cultured cells and mouse tumors.
HOBBY Reading, hiking, painting, and going to the beach |
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Isabel KoehlerUndergraduate Researcher, College of CharlestonSCIENCE Isabel is also researching metallothionein proteins and evaluating how they regulate cancer biology. She is evaluating various types of collagen through the uses of western blots and immunofluorescence on cultured cells and mouse tumors.
HOBBY Working out, reading, crafting, and spending time with friends |
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Undergraduate Researcher, College of Charleston
SCIENCE LuLu is evaluating tumor stemness properties of polyploid giant cancer cells in collaboration with Wendy.
HOBBY Working out, going to the beach, reading, and playing with her dogs |
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Kuma, Ph.D., M.S., M.B.A, Pharm.D.Hunter extraordinaireSCIENCE Current projects involve determining how to optimally acquire food. Hypotheses involve when humans are looking or otherwise distracted by small children. Eye contact is mandatory. Independent thought is overrated - team science is necessary.
HOBBY Greeting anyone, any time |
Principal Investigator
Joe Delaney, Ph.D.
Associate Professor
The Medical University of South Carolina
Department of Biochemistry and Molecular Biology
delaneyj [at ] musc.edu
Associate Professor
The Medical University of South Carolina
Department of Biochemistry and Molecular Biology
delaneyj [at ] musc.edu
Mentoring Philosophy
I am committed to ensuring the pursuit of science helps both the lab and the scientists involved in the research. Important aspects of scientific career building include not only acquiring cutting-edge technical skills, time management ability, and publications, but also being able to apply and obtain fellowships and grants. It is a high priority of mine to foster these pursuits for all levels of trainees: undergraduates to post-docs and beyond.
Team building in science also requires people to treat each other with courtesy and respect. In my lab, there are no dumb questions.
Each person here is mentored in a way which bests matches their personality. Introverts and extroverts are similarly welcome. Underrepresented minorities are strongly encouraged to apply for any open positions; I have mentored people from many backgrounds.
Team building in science also requires people to treat each other with courtesy and respect. In my lab, there are no dumb questions.
Each person here is mentored in a way which bests matches their personality. Introverts and extroverts are similarly welcome. Underrepresented minorities are strongly encouraged to apply for any open positions; I have mentored people from many backgrounds.
Education and Training
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Duke University
Post-doctoral training Mentor: Al La Spada, M.D., Ph.D. University of California San Diego Post-doctoral training Moores Cancer Center Mentor: Dwayne Stupack, Ph.D. Grant title: “Copy number alterations in low mutation cancer” |
University of Washington
Ph.D. in Molecular and Cellular Biology Mentor: Matt Kaeberlein, Ph.D. Thesis: "Elucidation of the molecular pathways of lifespan extension by dietary restriction in yeast" University of California: Berkeley B.S., Chemical Biology |